TRAMADOL: Use, Misuse & Abuse
Tramadol is a centrally acting narcotic analgesic.
Used in the treatment of moderate to severe pain.
MOA is not fully understood but research shows that it binds to the mu opoid receptor.
It inhibit the reuptake of norepinephrine and serotonin, hence blocking nociceptive impulses at spinal levels.
Possesses habituating properties leading to tolerance development, drug seeking behaviour and cravings
Tramadol is said to be abused if taken to achieve euphoria, mellowness and sense of well being.
Tramadol overdose can cause change in consciousness, decreased awareness, difficulty in breathing, lightheadedness and severe sleepiness.
Tramadol is an extended release drug, hence it is highly inappropriate to crush, break or chew drug. This practice can lead to exposure to a potentially fatal dose.
Taking tramadol with alcohol can lead to dangerous side effects or even death.
Tramadol is contraindicated for pregnant women and nursing mothers, as the drug can lead to a life threatening withdrawal symptoms in newborns
Tramadol is not for use to children younger than 12 years old
Taking tramadol with sedatives such as Diazepam, lorazepam, Valium and others can be very deadly.
TRAMADOL ABUSE IS BAD
Now that you know, let’s join hands and end the Abuse of Tramadol.
ANTI-DRUG MISUSE AND ABUSE PROGRAMME ( ADMAP)